Office: Steinman Hall 237
Tel: (212)650-5202
Fax: (212)650-8013
email: weinbaum@ccny.cuny.eduEducation:
B.A.E., 1959, Rensselaer Polytechnic Institute;
M.S. Applied Physics, 1960, Harvard Univ.;
Ph.D. Engineering, 1963, Harvard Univ.
Memberships:
Elected member National Academy of Engineering
Elected member National Academy of Sciences
Elected member Institute of Medicine of the National Academies
Fellow: ASME, AIMBE, APS.
Awards and Honors:
Gordon McKay Prize Fellow, Harvard University (1959-1961)
NSF Fellow, Harvard University (1961-1963)
Senior Fellow Scientific Research Council of Great Britain (1974)
NSF "Special Creativity" Award (1985)
Public Service Award of New York (1988)
Research Award of the European Society of Biomechanics (1994)
H.R.Lissner Award and Melville Medal of the ASME (1994)
Best Paper Award Bioengineering Division ASME (1995)
Melville Medal of the ASME (1996)
Whitaker Distinguished Lecture BMES (1997)
Richard Skalak Memorial Lecture UCSD (1999)
Classic Paper Award Heat Transfer Division ASME (2000)
Suhren Lecture Tulane University (2002)
Guggenheim Fellow in Molecular and Cellular Biology (2002)
Research Interests:
fluid dynamic and transport aspects of arterial disease
bioheat transfer
cellular mechanisms for mechanotransduction
bone fluid flow
microcirculatory exchange
transport in kidney proximal tubule
basic fluid mechanics
porous media flows
Professor Weinbaum has published more than 185 full length papers plus numerous shorter communications and conference papers. His research has involved important collaborations with other investigators and institutions. His joint studies with the UC San Diego have investigated the cellular origins of the permeability of arterial endothelium to low density lipoproteins, transport models for the arterial intima and the formation of subendothelial liposomes. His studies in bioheat transfer have examined the development of a fundamental bioheat equation to describe microvascular blood-tissue heat transfer (Weinbaum-Jiji equation) and the application of bioheat models to describe heat transfer in muscle tissue, limbs, rat tail and finger. His joint studies with the UC Davis have attempted to elucidate the structural pathways through the interendothelial cleft that determine capillary permeability and osmotic forces. His joint studies with S. C. Cowin have explored the cellular transduction mechanism by which bone cells detect mechanically induced strains and communicate these strains to the bone forming cells. His studies with Weill-Cornell Medical School have led to a new hypothesis for the mechanosensory mechanism that leads to the glomerulotubular balance in the kidney. He has also examined a wide variety of basic fluid mechanics problems that have arisen in biologically motivated applications. More than 30 of these papers have been published in the Journal of Fluid Mechanics.
Current Collaborators:
Y. Andreopoulos, Department of Mechanical Engineering, City College of New York
Recent and frequently cited publications:
You, L-D, Cowin, S.C., Schaffler, M.B., Weinbaum, S., "A Model for Strain Amplification in the Cytoskeleton of Osteocytes Due to Fluid Drag on Pericellular Matrix", J. Biomechanics, 34, 1375-1386 (2001)
Weinbaum, S., Guo, P., You, L., "A New View of Mechanotransduction and Strain Amplification in Cells with Microvilli and Cell Processes", Biorheology, 38, 119-142 (2001)
Zhao,Y., Chien, S., Weinbaum, S.,"Dynamic Contact Forces on Leukocyte Microvilli and their Penetration of the Endothelial Glycocalyx", Biophysical J., 80, 1124-1140 (2001)
Hu, X., Adamson, R.H., Liu, B., Curry, F.E., Weinbaum, S., "The Starling Forces that Oppose Filtration After Tissue Oncotic Pressure is Increased", Am. J. Physiol, Heart and Circulatory Physiology, 279, H1724-H1736 (2000)
Guo, P., Weinstein, A.M., Weinbaum, S., "A Hydrodynamic Mechanosensory Hypothesis for Brush Border Microvilli", American J. Physiology, Renal Physiology, 279, F698-F712, (2000)
Feng, J., Weinbaum, S., "Lubrication Theory in Highly Compressible Porous Media: The Mechanics of Skiing from Red Cells to Humans", J. Fluid Mechanics, 422, 281-317, (2000)
Weinbaum, S., "Models to Solve Mysteries in Biomechanics at the Cellular Level; A New View of Fiber Matrix Layers", 1997 Whitaker Distinguished Lecture, Annals of Biomed. Engr., 26, 1-17, (1998)
Huang, Y., Rumschitzki, D., Chien, S., and Weinbaum, S. "A Fiber Matrix Model for the Growth of Macromolecular Leakage Spots in the Arterial Intima", ASME J.Biomech.Engr., 116, 430-445 (1994). Best Paper Award Bioengineering Div. of ASME 1995/96, (Melville Medal, Highest Literature Award ASME)
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